Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester
PHYSOSTIGMINE
CAS: 57-47-6
Molecular Formula: C15H21N3O2
Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester - Names and Identifiers
Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester - Physico-chemical Properties
| Molecular Formula | C15H21N3O2 |
| Molar Mass | 275.35 |
| Density | 1.166±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 102-104 °C(lit.) |
| Boling Point | 418.29°C (rough estimate) |
| Flash Point | >100℃ |
| Water Solubility | Soluble in water (1:75), alcohol (1:10), chloroform (1:1), ether (1:30), and DMSO. |
| Appearance | Powder |
| Color | Off-white |
| Merck | 7384 |
| pKa | 6.12, 12.24(at 25℃) |
| Storage Condition | 2-8°C |
| Sensitive | Air & Light Sensitive |
| Refractive Index | 1.5600 (estimate) |
| Physical and Chemical Properties | Chemical properties colorless flake crystals, odorless. It gradually turns red in light, heat, air and trace metals. This product is unstable when encountering alkali, and it is hydrolyzed to form poisonous lentil phenol alkali, which is further oxidized to form red Iserin red. Mp105-106 ℃, specific rotation [α]17D-76 (1.3%, chloroform), [α]25D-120 (benzene). This product is easily soluble in dichloromethane, chloroform (1:1), ethanol (1:10), ether (1:30) and water (1:75). Toxic, LD50 (rat, oral) 4.5 mg/kg. |
| Use | Biochemical research, drug synthesis intermediates and anticholinesterase drugs. |
Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester - Risk and Safety
| Hazard Symbols | T+ - Very toxic |
| Risk Codes | 26/28 - Very toxic by inhalation and if swallowed. |
| Safety Description | S23 - Do not breathe vapour. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S25 - Avoid contact with eyes. |
| UN IDs | UN 1544 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | TJ2100000 |
| FLUKA BRAND F CODES | 8-10 |
| TSCA | Yes |
| Hazard Class | 6.1(a) |
| Packing Group | II |
| Toxicity | LD50 orally in mice: 4.5 mg/kg (Lynch, Coon) |
Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester - Upstream Downstream Industry
Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester - Security information
| toxic substance data | 57-47-6(Hazardous Substances Data) |
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: Physostigmine Visit Supplier Webpage Request for quotationCAS: 57-47-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
View History
Raw Materials for Methylcarbamic acid (3aS)-1,2,3,3a,8,8aα-hexahydro-1,3aα,8-trimethylpyrrolo[2,3-b]indol-5-yl ester
ZINC
2-Butenoic acid, 2-methyl-4-[[tris(1-methylethyl)silyl]oxy]-, (2Z)-
Benzenamine, 2-iodo-4-methoxy-N-methyl-
eseroline
(3aS,8aR)-5-methoxy-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole
METHYLISOCYANATE 1 X 500MG NEAT
2-Butenoic acid, 2-methyl-4-[[tris(1-methylethyl)silyl]oxy]-, (2Z)-
Benzenamine, 2-iodo-4-methoxy-N-methyl-
eseroline
(3aS,8aR)-5-methoxy-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole
METHYLISOCYANATE 1 X 500MG NEAT